In this note, we describe the managerial challenges undertaken by the Government of India for successfully eradicating the dreaded infectious disease polio. The success for polio eradication can be attributed to the detailed steps for (i) policy development, (ii) strategic planning, (iii) operational planning, and (iv) implementation/surveillance. The last case of polio in India was in West Bengal in January 2011. The following three years, there was no case of polio attack in India. The World health Organization declared India polio-free in March 2014.